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Hydrocodone is effective in the management of pain after augmentation mammoplasty but is associated with opioid-related adverse reactions. In a study of the potential opioid-sparing effect of a combination of hydrocodone + celecoxib one group of 50 patients had postoperative pain managed by hydrocodone and another 50 received celecoxib + hydrocodone and very long

Pain relief medicine.The latter also achieved superior pain relief and caused 53% less nausea.

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